Do you frequently suffer from heartburn or acid reflux, and are you managing to live a healthy lifestyle? If so, a new report in theJournal of the American Medical Associationstudy found that a single daily dose of Nexium 24HR is equally effective for managing heartburn than its equivalent of the equivalent of 14-Day Prevacid® (referred as Prilosec®) for managing acid reflux. The study, which was sponsored by Pfizer, found that only 14% of the 14-Day Prevacid® dose was equally effective in treating heartburn, compared to only 15% for Nexium 24HR. These findings highlight the potential benefits of Nexium 24HR for patients with heartburn, providing an alternative to Prilosec®.
Nexium 24HR and its equivalent Prevacid® (referred as Prilosec®) have received FDA approval in the United States for heartburn management. According to the study, one-year overall survival (OS) in patients with heartburn who were randomized to Nexium 24HR was approximately 40%. However, a small number of patients were also treated with Prilosec®, and the study found that this combination treatment is more effective than Prilosec® alone for treating heartburn in patients who are at risk for gastric ulcers or other adverse events.
Another report from thelooked at the efficacy of Nexium 24HR in reducing the rate of gastric ulcers in patients with heartburn. In this study, the overall gastric ulcer-free survival rate in patients with heartburn who were randomized to Nexium 24HR was significantly lower than that of patients who were not treated with Prilosec®.
The study also found that the most common adverse events were dry mouth, constipation, and constipation.
“The results of the current study reflect the potential benefits of Nexium 24HR in reducing heartburn,” says study author, Dr. Emily Johnson, of the University of Iowa. “Nexium 24HR offers a new option for patients with reflux-related acid reflux, and the results from this study suggest it is equally effective in treating acid reflux in patients at risk for gastric ulcers or other adverse events.”
A similar report fromThe Journal of the American Medical Associationshowed that the overall risk of gastric ulcers in patients who were treated with Prilosec® was 5.3% compared to 2.8% for patients who were not treated with Prilosec®. However, the study found that the study found that only 14% of the 14-Day Prevacid® dose was equally effective in treating heartburn, compared to only 15% for Nexium 24HR. The results showed that only 14% of the 14-Day Prevacid® dose was equally effective in treating heartburn than the equivalent of Prilosec® for patients who are at risk for gastric ulcers. This is an encouraging finding because this study, which was sponsored by Pfizer, included patients in a low risk group for gastric ulcers or other adverse events.”
“Our study suggests that the combination of Nexium 24HR and Prilosec® may be more effective than Prilosec® alone for managing acid reflux in patients with heartburn,” says Dr. Emily Johnson, professor of gastroenterology at the University of Iowa, who is the lead author on the study. “The study found that 14 days of treatment with Prilosec® alone is equally effective as treatment with Nexium 24HR.”
Johnson notes that the Nexium 24HR study found no significant difference between treatment groups in the rate of gastric ulcers, and she added that the study found that only 14% of the 14-Day Prevacid® dose was equally effective in treating heartburn than Prilosec® for patients who are at risk for gastric ulcers or other adverse events. However, this finding was not statistically significant.
“While the overall gastric ulcer-free survival rate was similar in the two groups, it is important to note that this study did not control for the possibility of gastric ulcers,” says Johnson. “Overall, the results of the current study suggest that the combination of Nexium 24HR with Prilosec® may be more effective than Nexium 24HR for treating acid reflux in patients who are at risk for gastric ulcers or other adverse events.”
Johnson is a consultant for Pfizer Consumer Healthcare, a division of Eli Lilly and Company.
References1. Johnson I.
Nexium 24HR Once Daily Dosing Tablets
Nexium 24HR 20mg (Gastro-o-Vaginal Cream) once daily, 60 Tablets (1 strip in total)
Suitable for treating the conditions like Menstrual Cycles, Vaginal Bleeding, Peyronie’s Disease, Postmenopausal Pain, Hot Flashes, Muscle Cramps, Oropharyngeal Artery thrombosis, Mucocutaneous Peyronie’s Disease
Suitable For Monotherapy
Precautions to be taken
General
Swallow the tablets whole with a glass of water.
Dosage
The recommended dose is one tablet every 24 hours as necessary (8-10 hours before sexual activity).
The maximum recommended dosing frequency is once a day. Do not take more than 1 tablet a day. The dose should be taken without food.
Consult your doctor or pharmacist if symptoms persist or severe reactions are frequent, or allergic reactions occur call your doctor immediately if any side effects appear.
Side Effects
Common side effects are headache, facial flushing, visual disturbances, nasal congestion, dizziness, and indigestion. Rare but serious side effects require immediate medical attention.
Maximum Daily Dosing
The dose is 24 hours and the frequency should be maintained at 2 or 3 doses per day.
Storage
Keep out of reach of children.
Share the product information on this page.Show moreShareNexium 24HR Tablets containing magnesium 24HR Once Daily Dose Tablets are a prescription medicine used for treating the following conditions:
Headache/Nausea/Flushing/Dizziness
Diarrhea/Stomach upset
Heartburn/Stuffy/Stomach upset
Diarrhea
Sore throat/Indigestion
Tremor
Nausea/Vomiting
Abdominal pain
Nasal congestion
Warnings and Precautions
Use as directed for the full duration of treatment. Do not use more than the recommended dose or prescribe a different medication as it may not results in a happy side effect.
Caution in Patients with Severe Heart Conditions
Hypersensitivity to the active substance or to any of the excipients. Avoid use in patients with hypersensitivity to H2-Receptor Antibodies, valproate or any other component of the medication.
Share the product information on this page if you would like to share more about your order.Share moreDo not use more than the recommended dose or prescribe a different medication as it may not provide a beneficial effect on existing patients with conditions that affect their stomach or intestine.
Share the product information on this page if you would like to share more about your new order.Nexium 24 Hour Heartburn Relief Medicine Nexium 24HR is a 24-hour esomeprazole tablet that contains the active ingredient esomeprazole. It is used to treat symptoms of heartburn, including burning, tarry stools, and gastric ulcers. Nexium 24HR works by reducing the acid in the stomach’s cells by blocking the production of pro-inflammatory substances in the stomach that causes the muscles in the stomachs to expand and the symptoms of heartburn are reduced.
Nexium 24HR contains Esomeprazole 24HR which is available by prescription from Dr Fox.
The recommended dose of Nexium 24HR is Esomeprazole 24HR which is taken orally up to mid-bulk which helps to reduce stomach acid in the treatment of heartburn.
Nexium 24HR is not recommended for use in children under 14 years of age.
Store at room temperature, away from moisture and infection. Do not store in the bathroom.
The most common side effects of Nexium 24HR include: Stomach upset, 14 days of symptom relief, 4 days of side effects, rebound, and food and drink can cause serious side effects. The most common side effects of Nexium 24HR are: Dizziness, 7 days of stomach pain, 7 days of constipation, 7 days of diarrhea, 2 days of constipution, 1 day of constipation, and 1 day of diarrhea.
Do not use Nexium 24HR if you are allergic to any of the ingredients of Nexium 24HR. Do not use if you have: • heartburn, nausea, headache, stomach pain, skin rash, itching, orVomiting, under 18 years old or a history of liver problems. Do not use if allergic to esomeprazole, lorazepam, omeprazole or rabeprazole, stomach or intestinal ulcer, or if you have pain in the chest, weakness or bruising is present, or you have diarrhoea. Do not use if you have: • fever above 38.5orphe measure (mild cases), kidney or liver problems, severe stomach pain, fever and chills, joint pain or swelling, severe chest pain, joint pains that do not make them serious, dark urine, abdominal pain, nausea, back pain, muscles or joints pain, dark yellow or brown urine, sore throat or stomach, persistent sore tongue or tongue, and persistent fever.
Talk to your doctor before taking if: • pain in your chest, weakness or bruising is present, or you have pain in your stomach or intestines, you have bleeding in your stomach, you have had a stroke or heart attack, you have had kidney or liver problems, you have had lacerations, you have had stomach ulcers or other bleeding disorders, or you have bleeding in the stomach. • you have had a heart attack, heart failure, heartburn, you have a stomach or intestinal bleeding disorder, you have had stomach ulcers, or you have stomach or intestinal bleeding. • you have had a bone fracture, or you have had a serious medical problem, including heartburn, nausea, vomiting, or diarrhea. • you are allergic to any other proton pump inhibitor tolistophene tolscene or tolmoride or you are on diuretics or have kidney or liver problems. • you have had a stomach ulcer, perforation or bleeding in the stomach, bleeding in the stomach or the stomach in a known or suspected you have stomach ulcers, bleeding in the stomach or intestines, broken, or bleeding that is dark yellow or brown, or have had stomach ulcers, or you have a broken, ulcerative colitis, or bleeding in the stomach or intestines that you have had stomach ulcers. • you have had a heart attack, heart or liver disease, heart problems such as heart failure, bleeding problems, blood circulation problems (such as liver problems or problems with blood circulation to the brain), kidney or heart failure, or have a history of pain and/or fever.
Nexium 24HRis a heartburn-fighting medication containing esomeprazole. It’s used to treat frequent heartburn and acid reflux by reducing stomach acid.
Active Ingredient:
Esomeprazole 20mg
Inactive Ingredients:
Product Specifications:
A-24 Heartburn – 7 days of 24hr
Product Benefits:
How to Use:
Take one tablet with a glass of water, one hour before your heartburn is expected to ache. The dose should be raised to three 20mg tablets a day, three days a week (depending on the patient’s response). Take the tablet as directed by your healthcare provider.
Storage:
Store in a cool, dry place away from direct sunlight
Things you should include in the prescription?
1. Any mention of additional storage steps
2. Where should I find a doctor in the U. S.
3. Where to find Nexium (the active ingredient)?
4. What should I know about the prescription?
Read MoreFor more information on acid reflux treatment, like any prescription, please check your doctor or pharmacist’s website.
Nexium 24HR is an over-the-counter product that contains the same active ingredient as Prilosec. You are advised to take Nexium 24HR if you are taking any prescription medication, including those that are not. You should not take Nexium 24HR if you are not sure
For more information about Nexium 24HR, including what it does and does not do, consult your doctor or pharmacist.
For more information about Nexium 24HR, like all prescription medications, including over-the-counter products, please inform your doctor or pharmacist of your medication prescription in the U.
Talk to your doctor, especially if you have any kidney or liver problems, to confirm the accuracy of the information contained in the U. prices.
Nexium 24HR may vary based on the amount of treatment you are taking. Typically, Prilosec is taken once a day with or without food. You are advised to take Nexium 24HR when you are directed to with food. However, the U. price for the 24HR 20mg dose is as follows:
If you would like more information on the correct amount to take, consult your doctor or pharmacist.
If you don’t want to wait, consult your doctor or pharmacist.
You are advised to avoid alcohol while taking this medication.
This product requires a valid prescription from your first heartburn treatment.
5. You should refer to the product instructions for additional information.
Nexium 24HR is suitable for adults and adolescents 15 years and over.
Take this medication by mouth as directed by your doctor, usually once a day. Swallow the tablets whole with a glass of water. Do not crush or chew the tablets. Take Nexium 24HR at least one hour before eating/taking treatment, to reduce the chances of side effects.
Nexium 24HR may not work for everyone, so talk to your doctor if you are pregnant or breastfeeding. Your doctor may occasionally check yourself for side effects after taking Nexium 24HR.
Nexium 24HR may not cause enough side effects, while some side effects may be more common or severe. If you experience any side effects that are not alleviated, you should urgent check your safety status.
Nexium 24HR may be used for up to 24 consecutive days, so if you are planning a longer treatment period, please talk to your doctor before taking it.